Very informative and educative powerpoint presentation on Rheumatoid arthritis . Slideworld.org
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Rheumatoid arthritis (RA) is a chronic systemic inflammatory disease predominantly affecting diarthrodial joints and frequently a variety of other organs.
Epidemiology
RA occurs worldwide in all ethnic groups.
Prevalence rates range from 0.3 to 1.5% in most populations, but frequencies of 3.5 to 5.3% have been found in several Native American tribes (Yakima, Chippewa, Inuit).
The peak incidence of onset is between the 4th and 6th decades, but RA may begin at any time from childhood ( Juvenile Chronic Arthritis) to later life.
Females are two to three times more likely to be affected than males.
Treatment Options
1. NSAIDS
2. STEROIDS
3. IMMUNOMODULATORS/IMMUNOSUPPRESSIVE AGENTS- MTX,HCQ,LEFLONEMIDE,SULPHASALAZINE,CYCLOPHOSPHAMIDE,AZATHIOPRINE, 4. MYCOPHENOLATE…..
5. ANTICYTOKINE DRUGS-TNF INH-ETANERCEPT,INFLIXIMAB,ADALIMUMAB
IL1 INH-ANAKINRA.
6. DO NOT COMBINE THE IL1 AND TNF INH.-SEVERE SEPSIS.
7. PLASMAPHERESIS -A new approach, pheresis across a column bound with staphylococcal protein A, the Prosorba column, has been approved for treatment of RA.
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